Nurse Alyssa Ogawa was a Starfleet officer aboard the USS Enterprise-D, and later, the USS Enterprise-E. She was one of the head nurses in the ship's sickbay, assigned there in 2367 as an ensign.

(TNG: "Future Imperfect", "Clues", "Identity Crisis")

Upon recommendation of Dr. Beverly Crusher, she was promoted to lieutenant junior grade in 2370.

(TNG: "Lower Decks")

Ogawa became a senior sickbay staff member, and would make reports in Crusher's absence.

(TNG: "Genesis")

Nurse Ogawa helped Dr. Crusher develop a way to stop the metamorphosis of the Tarchannen III aliens in 2367.

(TNG: "Identity Crisis")

She was also present during several surgeries involving the Trill ambassador Odan, which were the first Federation observations of the Trill symbiont.

(TNG: "The Host")

Alyssa was one of the many crewmembers to fall victim to the psychotrophically addictive effects of the Ktarian game..

(TNG: "The Game")

She was the nurse on hand for the first use of the genitronic replicator, during the risky surgery on Lieutenant Worf's spinal column.

(TNG: "Ethics")

Ogawa brought several pieces of medical equipment to the Enterprise bridge in order to monitor Captain Jean-Luc Picard's condition when he was knocked unconscious by a Kataan probe in late 2368.

(TNG: "The Inner Light")

In 2369, Ogawa assisted Dr. Crusher in performing an autopsy on Joshua Kelly, an engineer from the USS Yosemite.

(TNG: "Realm of Fear")

Shortly following this incident, she helped treat Deanna Troi after she became a receptacle for Ambassador Ves Alkar's psychic "waste."

(TNG: "Man of the People")

Ogawa took part in the relief effort to Tagra IV in 2369. She helped Amanda Rogers pack a shipment of tricorders for transport to the planet.

(TNG: "True Q")

Ogawa helped investigate the mysterious deaths of Doctors Jo'Bril and Reyga in 2369.

(TNG: "Suspicions")

Ogawa was one of the few junior officers who knew of the Cardassian defector Joret Dal's presence aboard the Enterprise.

(TNG: "Lower Decks")

In 2370, Ogawa treated Commander William T. Riker's back after he had rolled onto Cyprion cactus during a date with Rebecca Smith.

(TNG: "Genesis")

She also helped evacuate sickbay and care for injured crewmembers following the crash of the Enterprise-D saucer section on Veridian III in 2371.

(Star Trek Generations)

Ogawa was promoted to full lieutenant by 2373 and was posted to the new USS Enterprise-E. During the ship's trip to 2063, she helped evacuate sickbay after the Borg began to overrun the ship.

(Star Trek: First Contact)

Alyssa was friends with several other junior officers and civilians on the ship, including Sam Lavelle, Taurik, the late Sito Jaxa, and Ten Forward waiter Ben. The group often played poker together.

(TNG: "Lower Decks")

Beverly Crusher also considered Ogawa a friend and was concerned when she noticed Ogawa's future husband, Andrew Powell, with another woman in Ten Forward.

(TNG:"Imaginary Friend", "Attached" "Lower Decks")

Ogawa risked her own career when Dr. Crusher was relieved of duty for performing an autopsy on Dr. Reyga, violating the Ferengi death ritual and the Prime Directive.

(TNG: "Suspicions")

Ogawa briefly dated a fellow Enterprise-D crewmember in 2368. They took a holodeck trip to the Champs Elysees, and he invited her to Risa.

(TNG: "Imaginary Friend")

Ogawa dated Ensign Markson in early 2370, a relationship which became the subject of gossip between Dr. Crusher and Captain Picard.

(TNG: "Attached")

Ogawa began seeing Lieutenant Andrew Powell later that year. Andrew proposed to her, much to her surprise and delight. They announced the engagement after the evaluations.

(TNG: "Lower Decks")

The couple conceived a child shortly thereafter. The baby saved the life of the entire Enterprise crew when the ship was ravaged by Barclay's Protomorphosis Syndrome. Commander Data was able to extract natural immune barriers in the amniotic fluid from the pregnancy, which cured the condition.

(TNG: "Genesis")

She gave birth to the child in 2371.