Pit Bulls & Parolees depicts the day-to-day operations at the Villalobos Rescue Center (VRC), including rescues of abused, neglected, and abandoned dogs, and the center's efforts to adopt out dogs to new owners. The show's main focus is the interaction between Tia Maria Torres, founder of VCR, her dogs, and the parolees who work for her, during daily care and training duties, and pit bull rescue missions.