Michael Mancini, played by Thomas Calabro, is a fictional character from the 1990s prime time drama Melrose Place and the 2009 series of the same name.

Presented originally as an honest and devoted husband with a career driven mind-set, Michael became a very different character over the course of the series, turning into a notorious womaniser and schemer.

During the first series, Michael begins as a very dedicated husband to Jane, and the show chronicles their troubles as a couple. However, towards the end of the first series, Michael has an affair with Kimberly Shaw, causing Jane to file for divorce and kick him out of the apartment. Michael then moves in with Kimberly, but yet again has an affair, this time with Sydney Andrews, Jane's younger sister.

In the spin-off/revival of the show, Michael is shown to have married a woman named Vanessa, and has a son named David, one of the main characters. He is still a very unfaithful man, cheating on his wife with both Sydney (prior to her death) and her daughter, Violet Foster.

Michael Mancini is notable for being the only character who was present for the show's entire run.