Ephram Brown is a piano genius that moves from Mew York City to the town of Everwood with his father, Andy Brown, and sister, Delia Brown, after the death of his mother in his sophomore year of high school. Ephram does not get along with this father very well because Andy was never really much of a father while his mother was alive.

When he arrives in Everwood, Ephram is the new kid on the block in a town and school of people who have known each other for years; he befriends Amy Abbott, and helps her deal with her comatose boyfriend, Colin. Ephram convinces his father to perform brain surgery on Colin twice, but Colin dies during the second attempt. Then Ephram assists Amy get through the death of Colin, and forms a strong friendship with her. He also befriend Amy's older brother, Bright. Ephram falls in love with Madison, a 20 year old college student employed by Andy as a babysitter. Ephram has his first time with Madison, but their relationship doesn't work out because of the 4 year age difference. Madison leaves town.

Ephram goes to New York for the Juliard summer program the summer before his senior year. He professes his love for Amy just before he leaves and she accompanies him to New York for a little while. Towards the end of his senior year Ephram goes back to New York to audition for Juliard for college. While in New York he meets up with Madison and she tells him that she left town because she had been pregnant with his baby, but she gave him up for adoption. Ephram goes back to tell his father but hears that Andy not only knew about the pregnancy, but asked Madison not to tell Ephram. The anger and stress of finding out about the child he didn't know he had and the lie his father had told him sent Ephram into a tailspin. He missed his Juliard audition and left his father's house for a while. Then, when Amy revealed that she also knew about the pregnancy, Ephram sold his piano and went to Europe. While in Europe Ephram forgave his father and realized he was still in love with Amy. Ephram attended Everwood Community College for his first year of college and lived with Bright.