Set in a middle-class African American neighborhood in Washington, DC. The show deals with the life of Clifton Curtis, a 20ish year old who was employed at Oscar's Barber Shop, which he has now inherited from his late father. Clifton likes his days as a bachelor, but his well intentioned mother "Momma" Curtis, would prefer he settles down and takes a bride.
- Ted Lange as "Junior" had the show's one catchphrase, which he said each time he entered a scene: "Oo-wee! I got it, I got it, and I've got to ree-port it."
- In 1987, a pilot for a syndicated revival series called That's My Mama Now! (1986) (TV) starring Ted Lange was produced but it was not picked up.
- Ed Bernard originally played the role of Earl Chambers but was replaced by Teddy Wilson. Wilson met and eventually married Joan Pringle when she replaced Lynne Moody in the role of Tracy. However Bernard and Pringle would eventually work together shortly after on The White Shadow.
- Both Theresa Merritt and Teddy Wilson were the only two cast members of The Furst Family of Washington to make the transition to this reboot and renaming of the series.
- "That's My Mama" was among the first batch of shows produced by Columbia Pictures Television in 1974 after they changed their name from Screen Gems. A shortened version of the Screen Gems "S from Hell" jingle by Eric Siday was heard over the new logo (nicknamed "The Pretzel" from the way the C,P, and T in the logo melded together); two years later that was replaced by the Columbia Pictures Television "Sunburst" logo, with a more pleasant synthesizer jingle composed by Suzanne Cianni.
- The bit part of "Augusta" was played by the late great Ernestine Wade, who was the eternal suffering wife of the 'Kingfish' on the "Amos & Andy Show"(1951-1955). This would be 1 of 2 bit appearances on this classic series and would be her final appearances as an actress as she passed away in 1983 at the age of 76 of unknown causes.
- Last show of the series.