Samantha "Sam" Newly (played by Christina Applegate), is a hit-and-run victim who awakens after being in a coma for eight days, only to find she has amnesia. With no memories of the past, she must rediscover everything about her life and herself by looking for clues from her past. Sam discovers that she wasn't a very nice person...
Last Episode02x20 With This Ring Aired: Jul. 23, 2009
On Andrea's wedding day to gay pro-basketball player Tony Dane, Sam finds herself at a crossroads and must choose between being with Winston …
Samantha Who?: Season 2, Episode #20 - With This Ring
Sam has retrograde amnesia and sets out to rediscover herself.
Samantha Who?: Season 2, Episode #19 - The Other Woman
Sam tries to be cordial to Winston Funk's ex-wife Gigi.