- Movie Goof (factual errors): Early in the movie, the science teacher Larry White (Rainn Wilson) tells his class that James D. Watson and Francis Crick "cracked" the genetic code. This is untrue. While Watson and Crick's discovery of the double-helical structure of DNA helped explain how genes were replicated during cellular or viral reproduction, Marshall Nirenberg, Har Gobind Khorana, and Robert Holley actually did the research that correctly interpreted the genetic code, for which these three scientists received the 1968 Nobel Prize in Physiology and/or Medicine.
- Movie Goof (continuity error): In the scene (from 04:32 to 05:55 on the DVD) where Noah Wilder is in his bedroom, wearing pajamas and playing a video game, his father comes home late and visits with him. In one shot when Noah throws his video game controller down, you can see he is bare-foot. In the very next shot from a different angle, as his father is talking to him, Noah is wearing slippers. (Note: This is a "full-frame-only goof", not visible in the wide screen versions, because their frames were made by cropping 41.7% of the height of the spherical 35 mm film negative frames, cutting Noah's bare feet out of the frame, although his slippers can still be seen at 04:41. The full height of the negative is shown in the full frame version, leaving Noah's bare feet in their frames.)
- When Noah first controls a spider at the beach house (at 19:30), director Robert Shaye mentions in the commentary that Visual Effects Supervisor Eric Durst "got hold of the special effects house in Australia that did all of the visual effects for Charlotte's Web - they happened to have the computer program for making spiders crawling on webs."
- The theme song to the movie, "Hello (I Love You)" (not to be confused with the similarly-titled classic song by The Doors) is a rare one-off song by former Pink Floyd frontman Roger Waters, whose songs are usually part of concept albums. Waters worked with composer Howard Shore, so that the song's melody is a leitmotif in the film, as well as dovetailing well with the rest of the film's score. Waters commented, "I think together we've come up with a song that captures the themes of the movie - the clash between humanity's best and worst instincts, and how a child's innocence can win the day." Incidentally, the film touches on themes that Waters' album Amused to Death was concerned with, while the song's lyrics reference Waters' Pink Floyd works Dark Side of the Moon and The Wall, as well as Waters' solo album Radio KAOS.
View All: Trivia - Goofs - Quotes
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